Cleveland, Ohio clinic performs US’s first face transplant

Thursday, December 18, 2008

A team of eight transplant surgeons in Cleveland Clinic in Ohio, USA, led by reconstructive surgeon Dr. Maria Siemionow, age 58, have successfully performed the first almost total face transplant in the US, and the fourth globally, on a woman so horribly disfigured due to trauma, that cost her an eye. Two weeks ago Dr. Siemionow, in a 23-hour marathon surgery, replaced 80 percent of her face, by transplanting or grafting bone, nerve, blood vessels, muscles and skin harvested from a female donor’s cadaver.

The Clinic surgeons, in Wednesday’s news conference, described the details of the transplant but upon request, the team did not publish her name, age and cause of injury nor the donor’s identity. The patient’s family desired the reason for her transplant to remain confidential. The Los Angeles Times reported that the patient “had no upper jaw, nose, cheeks or lower eyelids and was unable to eat, talk, smile, smell or breathe on her own.” The clinic’s dermatology and plastic surgery chair, Francis Papay, described the nine hours phase of the procedure: “We transferred the skin, all the facial muscles in the upper face and mid-face, the upper lip, all of the nose, most of the sinuses around the nose, the upper jaw including the teeth, the facial nerve.” Thereafter, another team spent three hours sewing the woman’s blood vessels to that of the donor’s face to restore blood circulation, making the graft a success.

The New York Times reported that “three partial face transplants have been performed since 2005, two in France and one in China, all using facial tissue from a dead donor with permission from their families.” “Only the forehead, upper eyelids, lower lip, lower teeth and jaw are hers, the rest of her face comes from a cadaver; she could not eat on her own or breathe without a hole in her windpipe. About 77 square inches of tissue were transplanted from the donor,” it further described the details of the medical marvel. The patient, however, must take lifetime immunosuppressive drugs, also called antirejection drugs, which do not guarantee success. The transplant team said that in case of failure, it would replace the part with a skin graft taken from her own body.

Dr. Bohdan Pomahac, a Brigham and Women’s Hospital surgeon praised the recent medical development. “There are patients who can benefit tremendously from this. It’s great that it happened,” he said.

Leading bioethicist Arthur Caplan of the University of Pennsylvania withheld judgment on the Cleveland transplant amid grave concerns on the post-operation results. “The biggest ethical problem is dealing with failure — if your face rejects. It would be a living hell. If your face is falling off and you can’t eat and you can’t breathe and you’re suffering in a terrible manner that can’t be reversed, you need to put on the table assistance in dying. There are patients who can benefit tremendously from this. It’s great that it happened,” he said.

Dr Alex Clarke, of the Royal Free Hospital had praised the Clinic for its contribution to medicine. “It is a real step forward for people who have severe disfigurement and this operation has been done by a team who have really prepared and worked towards this for a number of years. These transplants have proven that the technical difficulties can be overcome and psychologically the patients are doing well. They have all have reacted positively and have begun to do things they were not able to before. All the things people thought were barriers to this kind of operations have been overcome,” she said.

The first partial face transplant surgery on a living human was performed on Isabelle Dinoire on November 27 2005, when she was 38, by Professor Bernard Devauchelle, assisted by Professor Jean-Michel Dubernard in Amiens, France. Her Labrador dog mauled her in May 2005. A triangle of face tissue including the nose and mouth was taken from a brain-dead female donor and grafted onto the patient. Scientists elsewhere have performed scalp and ear transplants. However, the claim is the first for a mouth and nose transplant. Experts say the mouth and nose are the most difficult parts of the face to transplant.

In 2004, the same Cleveland Clinic, became the first institution to approve this surgery and test it on cadavers. In October 2006, surgeon Peter Butler at London‘s Royal Free Hospital in the UK was given permission by the NHS ethics board to carry out a full face transplant. His team will select four adult patients (children cannot be selected due to concerns over consent), with operations being carried out at six month intervals. In March 2008, the treatment of 30-year-old neurofibromatosis victim Pascal Coler of France ended after having received what his doctors call the worlds first successful full face transplant.

Ethical concerns, psychological impact, problems relating to immunosuppression and consequences of technical failure have prevented teams from performing face transplant operations in the past, even though it has been technically possible to carry out such procedures for years.

Mr Iain Hutchison, of Barts and the London Hospital, warned of several problems with face transplants, such as blood vessels in the donated tissue clotting and immunosuppressants failing or increasing the patient’s risk of cancer. He also pointed out ethical issues with the fact that the procedure requires a “beating heart donor”. The transplant is carried out while the donor is brain dead, but still alive by use of a ventilator.

According to Stephen Wigmore, chair of British Transplantation Society’s ethics committee, it is unknown to what extent facial expressions will function in the long term. He said that it is not certain whether a patient could be left worse off in the case of a face transplant failing.

Mr Michael Earley, a member of the Royal College of Surgeon‘s facial transplantation working party, commented that if successful, the transplant would be “a major breakthrough in facial reconstruction” and “a major step forward for the facially disfigured.”

In Wednesday’s conference, Siemionow said “we know that there are so many patients there in their homes where they are hiding from society because they are afraid to walk to the grocery stores, they are afraid to go the the street.” “Our patient was called names and was humiliated. We very much hope that for this very special group of patients there is a hope that someday they will be able to go comfortably from their houses and enjoy the things we take for granted,” she added.

In response to the medical breakthrough, a British medical group led by Royal Free Hospital’s lead surgeon Dr Peter Butler, said they will finish the world’s first full face transplant within a year. “We hope to make an announcement about a full-face operation in the next 12 months. This latest operation shows how facial transplantation can help a particular group of the most severely facially injured people. These are people who would otherwise live a terrible twilight life, shut away from public gaze,” he said.

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How To Decide Which Graphic Design Software To Buy

By Brian Scott

Long gone are the days when a graphic designer’s tools were pen, pencil, brush, exacto knife and illustration board. Today’s designer relies almost exclusively on graphic design software which is both expensive and constantly changing. At some point or other, the designer has to decide to upgrade his or her present software or change to another brand. And, then the designer must learn all the new functions of this version of software. If the program interface changes then the learning curve for the design professional can be very steep and costly. On top of that, there’s different graphic design software for desktop publishing, web design, illustration, and photography.

For much of the last decade, the desktop publishing arena was ruled by Quark Express. (Before that Adobe’s PageMaker had been King of the Mountain.) Over the past few years, Adobe has been making a serious bid to regain its preeminence in desktop publishing with In Design. If Adobe squashes Quark it will pretty much have a monopoly in graphic design software, having already swallowed up Macromedia and much of its other competition.

At the end of 2005, Adobe concluded its acquisition of Macromedia which made it the owner of Dreamweaver – usually acclaimed as one of the best (and sometimes the most difficult to use) web design software available. Dreamweaver has few challengers in the arena of professional web design. Microsoft’s Front Page still provides services for non-professionals and some professionals who are old-time PC users. Mostly though, Adobe, with the acquisition of Dreamweaver, has attained a semi-monopoly here as well.

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In graphic design software for photography there’s only one acknowledged leader – Adobe Photoshop. While other programs exist for the casual user, for the professional photographer Photoshop is the digital darkroom. Other companies exist by producing “plug-in’s for Photoshop, until Adobe buys them.

What about graphic design software for illustration? Again, Adobe is the leader. With Adobe Illustrator used and recognized by the most professionals it usually wins hands down against the competition. And, it’s not always which program is the easiest to use or has the most functions. It is which one is the most compatible in the most places. Corel Draw, Canadian illustration competitor to Illustrator is acknowledged by many to be easier and have more functions – but the files are hard to use anywhere but with Corel. So that limits across program functionality and thus its popularity.

One of the reasons InDesign is gaining so much ground is the ease of use with all of the other graphic design software programs in the Adobe family. You can move between them quickly and smoothly. Adobe now packages them as its Creative Suite and so it becomes one-stop shopping.

But, what will happen if Adobe becomes King of the Mountain? Without challengers, will it maintain the same quality and drive for excellence? And what will happen to the price? Will it even out or just continue upward. If you’re the only ballpark, you can charge whatever rent you want?

About the Author: Visit Brian Scott’s website,

FastCashDesign.com

and learn about freelance graphic design and how to launch a successful

Graphic Design Career

.

Source:

isnare.com

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Arson charge for man who cleaned home with gasoline

Wednesday, April 8, 2009

Ernest Krajniak from Chilton, Wisconsin in the United States has been charged with arson after a lit cigarette ignited gasoline soaked clothes, setting his apartment ablaze.

On Friday April 3, Krajniak, 47, cleaned his entire apartment with about five gallons of gasoline, wiping everything down with the soaked clothes. After he was finished, he piled the soaked clothes in the center of his bedroom, lit a cigarette and then threw what was left of the still lit cigarette, into the pile.

Krajniak never called the fire department and never pulled the alarm. Instead he yelled ‘fire’ a few times then walked to the police station where an ambulance took him to a local hospital for the treatment of minor burns. The fire department later arrived to put out the blaze and his apartment was extensively smoke damaged. 11 other apartments were also damaged, leaving the occupants without a place to stay for at least a week.

“I should have never used that,” said Krajniak during a court appearance on Monday. He admitted to knowing that gasoline was highly flammable. He was arrested and his bond has been set a US$2,500. Krajniak’s next court appearance is scheduled for Monday, April 13. According to WISinfo.com, Krajniak has no prior criminal record.

The careless smoking of cigarettes has been blamed for thousands of fires across the U.S. In January 2008, an unnamed elderly woman in Buffalo, New York was receiving oxygen for medical problems in her home and lit a cigarette and began to smoke it. The oxygen coming from her mask then facilitated the ignition of her clothing, setting her on fire.

In the U.S. in 2002, only 4% of all residential fires were reportedly caused by smoking materials. These fires, however, were responsible for 19% of residential fire fatalities and 9% of injuries. The fatality rate due to smoking is nearly four times higher than the overall residential fire rate; injuries are more than twice as likely. Forty percent of all smoking fires start in the bedroom or living room/family room; in 35% of these fires, bedding or upholstered furniture are the items first ignited.

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Wikinews interviews Democratic candidate for the Texas 6th congressional district special election Daryl Eddings, Sr’s campaign manager

Tuesday, April 20, 2021

Wikinews extended invitations by e-mail on March 23 to multiple candidates running in the Texas’ 6th congressional district special election of May 1 to fill a vacancy left upon the death of Republican congressman Ron Wright. Of them, the office of Democrat Daryl Eddings, Sr. agreed to answer some questions by phone March 30 about their campaigns and policies. The following is the interview with Ms Chatham on behalf of Mr Eddings, Sr.

Eddings is a federal law enforcement officer and senior non-commissioned officer in the US military. His experience as operations officer of an aviation unit in the California National Guard includes working in Los Angeles to control riots sparked by the O. J. Simpson murder case and the police handling of Rodney King, working with drug interdiction teams in Panama and Central America and fighting in the Middle East. He is the founder of Operation Battle Buddy, which has under his leadership kept in touch with over 20 thousand veterans and their families. He was born in California, but moved to Midlothian, Texas. He endeavours to bring “good government, not no government”. Campaign manager Faith Chatham spoke to Wikinews on matters ranging from healthcare to housing.

An Inside Elections poll published on March 18 shows Republican candidate Susan Wright, the widow of Ron Wright, is ahead by 21% followed by Democrat Jana Sanchez with 17% and Republican Jake Ellzey with 8% with a 4.6% margin of error among 450 likely voters. The district is considered “lean Republican” by Inside Elections and voted 51% in favour of Donald Trump in last year’s US presidential election. This is down from 54% for Trump in 2016’s presidential election, the same poll stated.

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How To Acquire Office Space In Champaign, Il For Your Small Business

byadmin

As an Illinois start-up company, you are limited in the amount of capital you possess to get the doors to your business open. In the initial stages, it could become impossible for you to buy a property outright and to be honest until your project is a proven success, it’s better to weigh your options. For this exact reason, you should review the opportunities available for renting an office space.

What Can You Expect

Your first step in renting an Office Space in Champaign IL is to establish the dimensions you need. This assessment is based on if clients visit the location or if you plan to set up an office from which you’ll operate. A smaller business could utilize less space and ultimately save a considerable amount of capital in these beginning phases.

You won’t sign a long-term lease. Most business owners when faced with the decision to rent become fearful about the commitment associated with a six-month or yearly lease. As their company grows, they’ll need a larger space, and if they are under contract for this long of a duration, it presents a conflict. This is why offices are available on a month-to-month basis for businesses. It provides more flexibility.

The Benefits of Working with a Leasing Agency

In addition to the office space, you could acquire additional services. These services include telephony systems, network connections, and a virtual office. For a small business owner, these are prime opportunities to save. It also reduces the amount of time needed to set up shop. Discuss these services with your chosen leasing agency to determine if they are advantages. When they are you can include them in your rental agreement.

Small business owners need as many advantages as they can get. This is more than relevant when they seek an Office Space in Champaign IL. They need to find a location quickly to grow their new company. By choosing a location in their target area, they can increase their client base quickly and efficiently. They could also get set up at a more rapid pace, by acquiring existing services within these locations. Small business owners who want to review available rentals should Contact Business Technology Centertoday.

Wikinews interviews 2020 US Libertarian Party presidential candidate Adam Kokesh

Saturday, September 7, 2019

Adam Kokesh, an Iraq War veteran, activist, radio show host, and currently a candidate for the US Libertarian Party’s 2020 presidential nomination, spoke with Wikinews to discuss his background, political positions, and campaign for President of the United States.

Kokesh, who hails from Arizona, has been active in the anti-war movement since returning home from combat in Iraq. After an initial honorary discharge from active duty with the US Marine Corp in 2006, Kokesh was given a general discharge from the Marine Forces Reserve in 2007 after images of him wearing his uniform while participating in a protest with the Iraq Veterans Against the War were published in The Washington Post. Kokesh has also been involved in demonstrations in support of free speech, gun rights, and marijuana decriminalization. Some of these activities have resulted in his arrest. Kokesh previously hosted a show on RT and currently hosts a show on internet radio.

Politically, Kokesh supported the 2008 and 2012 presidential campaigns of Ron Paul. He was a featured speaker at Paul’s Rally for the Republic in 2008. Kokesh ran for US Congress as a Republican in 2010 in New Mexico and for US Senate in Arizona in 2018. He announced his 2020 candidacy in 2013 during a jailhouse interview. He has based his campaign on the pledge to begin “dissolving the federal government in a peaceful, orderly manner” and to resign as president and take the title of “Custodian of the Federal Government.”

Other contenders for the Libertarian Party’s 2020 presidential nomination include former Libertarian Party Vice Chairman Arvin Vohra, businessman John McAfee, and New Hampshire state representative Max Abramson. Congressman Justin Amash and former Rhode Island governor and US Senator Lincoln Chafee are both reportedly considering runs. Former New York gubernatorial candidate Larry Sharpe and former Massachusetts governor William Weld were both previously considered potential candidates but Sharpe suggested he would not run and Weld has decided to run in the 2020 Republican Party presidential primaries, challenging President Donald Trump.

With accredited Wikinews reporter William S. Saturn, Kokesh details his background and activism, his thoughts on the Libertarian Party, the Presidency of Donald Trump, and the goals for his campaign and presidency.

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Automobile sales in the United States down sharply

Tuesday, February 3, 2009

Sales of automobiles in the United States fell as much as 35% in January, compared to the same month a year ago, as manufacturers reported their January sales.

Ford Motor Company NYSEF sales dropped 42% last month from the previous year. General Motors NYSEGM reported a 49% decline. Chrysler was hardest hit among the domestically owned manufacturers with a plunge of 55%.

The decline in sales has not been limited to just US manufacturers. Japanese automaker Toyota NYSETM reported a 32% drop in US sales from a year earlier, Nissan MotorsNASDAQNSANY dropped 30%, and Honda NYSEHMC sales dropped 28%.

Subaru and South Korean Hyundai Motor Company LSEHYUD were two of the few auto firms that reported an increase in sales. They posted gains of eight and fourteen percent, respectively.

On an annual basis, sales overall have also been plummeting. Industry-wide US car sales dropped 18% last year to 13.2 million automobiles.

GM announced today that it will offer voluntary buyouts to 22,000 employees in the US, in an effort to reduce its expenditures.

Last month, GM and Chrysler were given loans worth US$17.4 billion from the government after they warned of imminent bankruptcy.

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Don’t Forget To Ask Your Landlord These Questions Before You Sign Your Lease

Many apartment renters are so anxious to get into their new apartment home they forget to ask some very important questions that everyone should ask before they sign their lease. It is extremely important to have your questions ready when you speak with the leasing agent or landlord.

You will be able to gauge how quickly your future landlord may move on issues you may have in the future; based on how fast he or she will be able answer your questions. There is nothing better than having a fast moving landlord or management company.

We have put together a list of questions and ideals that may make your apartment decision easier and more efficient.

Questions Regarding Rent

When is rent due and how much is it? What if you are late? Do you have a grace period?

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Many properties will allow you to have a grace period of a few days. After that late fees will accrue daily.

Lease Terms

What is the length of my lease? Can I have a shorter lease term for the same price? What happens after my lease is over? Does it automatically renew or does it revert to a month by month basis?

Deposits and Fees

What types of deposits must I pay before I move in? Is the deposits refundable or will I just receive a portion back when I move out. Once I do move out how long will it take before I do receive the deposit back.

Most deposits range from a few hundred dollars to one month’s rent. By Texas law your management company or landlord must mail out the deposit refund within 30 days. If your apartment allows pets, you will have to pay an additional pet deposit. Be sure and ask how much of the pet deposit is refundable. Do they automatically take out a certain amount for a cleaning fee after you move out?

Are Utilities Included

Most utilities that you are responsible for include water and electricity. If your utilities are not included in the rent, ask your landlord for the average cost the previous tenant incurred. This should give you an idea of what you will be responsible for.

Repairs

If something breaks, are you responsible for the repairs.

Most properties will fix anything that breaks not a result of any actions by you. A great question to ask is who replaces the light-bulbs that go out.

Good luck renting your new apartment home.

Article Source: sooperarticles.com/real-estate-articles/leasing-articles/dont-forget-ask-your-landlord-these-questions-before-you-sign-your-lease-40648.html

About Author:

Andrew Reichek is an apartment locator. He helps people find Bellaire apartments. If you need help in Dallas please look for Valley Ranch apartments for rent. Other popular places include Mequite Apartments.Author: Andrew Reichek

Woman killed on amusement park ride in New York

Sunday, July 1, 2007

A young woman was killed Friday night after an accident occurred on a gyrating ride at the Playland amusement park in Rye, New York in the United States. The woman, Gabriela Garin, was a worker at the amusement park, and had worked there for the past seven years.

The accident occurred near the end of Garin’s shift; as she was loading riders onto the ride. The ride’s new operator, unaware of Garin’s presence, started the ride while Garin was still on it. The new operator then noticed Garin, and shut the ride down in 20 seconds, but Garin had already been ejected from the ride and killed, according to a park spokesperson.

The ride is an attraction that spins people around in two-seat cars, inside a darkened tent to flashing lights and music.

This incident is not the first in the ride’s history. In 2004, a seven-year-old from Connecticut managed to free herself from the ride’s restraining bars, and climb onto the front edge of her seat. She fell soon after the ride started. A safety precaution was put in place after this incident, however, the spokesperson acknowledged that it was not followed when Garin was killed.

The company which owns the ride shut it down, along with two other rides it owns at the park.

This is the fourth fatality in the park’s history. The park features more than 50 rides, a pool, and a beach. It attracts more than 1 million visitors annually.

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Canada’s social insurance assets pass $140 billion in fourth quarter

Sunday, February 13, 2011

With a fourth-quarter investment earnings of $3.9 Billion CAD, largely driven by stock market rises, the Canada Pension Plan’s (CPP) assets rose to $140.1 Billion reported the CPP Investment Board on Thursday.

Rate of return for the quarter netted three percent, bringing the first nine months of the fiscal year to 8.3%. The fund’s broad exposure to equities, in concert with a good quarter for stocks both in Canada and internationally, was largely to be credited according to CEO David Deneson.

The assets value rose from $127.6 Billion March 31st 2010, to $138.6 B on September 30th, to $140.1 B December 31st. The $3.9 B investment earnings, 3.58 of which came from the 54% of the portfolio in equities, was partially offset by seasonal outlays of $2.4 B to plan members.

The fund was very active throughout the calendar year, and particularly active in infrastructure, real estate, and private equity. As part of a consortium they completed the $4.8 B purchase of UK-based Tomkins plc, as well as purchasing Australian-based Intoll for $3.4 B thus acquiring a 30% stake in the 407 Express Toll Route (ETR) near Toronto — which they expanded purchasing a further 10% stake from Spain’s Concesiones de Infraestructuras de Transporte, S.A. (CINTRA). They acquired a 25% equity stake in Westfield Stratford City, a retail complex adjacent to London’s Olympics venue, among many real estate ventures.

The CPP fund covers every province except Quebec, whose Caisse de Depot et Placement du Quebec is the only larger pension fund in Canada. The five-year annualised investment rate of return for the CPP reserve fund was 3.5%, its 10-year rate of return was 5.6%, at the close of 2010. The fund was established in 1997.

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