Thursday, February 22, 2007

Denial. Anger. Bargaining. Depression. Acceptance.

Originally formulated in 1973 by Elisabeth Kübler-Ross, these five stages are well-known to many as the “Five Stages of Grief“. However, despite their familiarity, the five-stage theory had remained untested empirically, until Paul K. Maciejewski, Ph.D., assistant professor of psychiatry at the Yale University School of Medicine and the Yale Bereavement Study completed several years of research, findings for which were published in the February 21 issue of the Journal of the American Medical Association (JAMA).

According to Dr. Kübler-Ross’s theory, denial is the first and most defining indicator of grief. The Yale Bereavement Study’s findings, in contrast, show acceptance to be the most common indicator, and yearning the strongest negative indicator.

The authors explain, “Disbelief decreased from an initial high at one month postloss, yearning peaked at four months postloss, anger peaked at five months postloss, and depression peaked at six months postloss. Acceptance increased steadily through the study observation period ending at 24 months postloss.”

Study author Holly Prigerson, associate professor of psychiatry at Harvard Medical School and director of the Dana-Farber Cancer Institute‘s Center for Psycho-Oncology and Palliative Care Research, says, “This would suggest that people who have extreme levels of depression, anger or yearning beyond six months would be those who might benefit from a better mental health evaluation and possible referral for treatment.”

The Yale Bereavement Study followed the progress of 233 participants from January 2000 through January 2003 who had lost family, most often a spouse, and was funded by the National Institute of Mental Health, the National Cancer Institute, the National Institute of Neurological Disorders and Stroke, the Center for Psycho-Oncology and Palliative Care Research, Dana-Farber Cancer Institute, and Women’s Health Research at Yale University.

Friday, September 14, 2007

British bank Northern Rock received emergency loans from the Bank of England yesterday, as it felt the effects of the financial crisis originating in the U.S. subprime mortgage market. Queues formed outside branches as many customers sought to withdraw their savings, and shares fell heavily.

Northern Rock, based in Newcastle, is one of the UK’s largest mortgage lenders, with total assets and loans of £113 billion. Pressure has grown on the bank as other institutions have become less willing to buy mortgage debt, following the American subprime crisis.

The support from the central bank was authorised by the Government and the Financial Services Authority, following assurances that the problems were temporary and the bank remained solvent. Some current mortgages are being used as collateral. The lending is an “unlimited” facility, at an interest rate higher than the base rate. Chancellor of the Exchequer Alistair Darling, speaking on Radio 4’s Today programme, encouraged customers to carry on as normal, stating that “Northern Rock will be able to carry on its business”.

Northern Rock chief executive Adam Applegarth also called for calm, but customers were seen queuing outside branches across the country to withdraw money. It is reported that the company website also crashed under the demand.

Shares in the bank fell 31.5% on Friday, down almost 60% from their highest value this year. Applegarth admitted that profits would be hit, but stated that the bank would adapt to the changes. Shares in other lenders also fell, with Paragon being the most extreme, dropping almost 17%. The FTSE 100 closed down 1.17% (74 points) following a recovery in the afternoon.

The last time the Bank of England acted as “lender of last resort” in this way was in 1973, after the collapse of Cedar Holdings.

Friday, August 26, 2005

A Midland, Michigan hotel was temporarily quarantined Thursday night when a letter with suspicious white powder was opened at the Ashman Court Hotel on Main Street.

A hotel employee is said to have opened the letter around 16:00 UTC time on Thursday. Shortly after, the police, FBI and HAZMAT teams were called to the building. Preliminary results from FBI tests showed that the envelope did not contain the deadly bacteria anthrax, as first thought.

The letter contained “a threat” according to local reports, however details were not released. It is also unknown as to what substance the white powder is.

This is the second anthrax scare on the city this year, exactly four months ago the Midland Daily News office, located across the street to the hotel, was sent a similar envelope with suspicious powder. It is not known if the two cases are related or not.

Wednesday, December 7, 2005

Australian researchers say they have scientifically proven that stress causes sickness. The Garvan Institute in Sydney has discovered that a hormone, known as neuropeptide Y (NPY) is released into the body during times of stress. Their findings show the hormone can stop the immune system from functioning properly.

“Neuropeptide Y is one of those hormones that gets unregulated or released from neurones when stressful situations occur…it’s known for example that it regulates blood pressure and heart rates so your heart rate goes up but it hasn’t been known that it actually can affect immune cells as well,” said Professor Herbert Herzog, one of the researchers.

Herzog feels it is good to finally have proof of something people have suspected for so long.

“Now we have proven without doubt that there is a direct link and that stress can weaken the immune system and that makes you more vulnerable when you for example have a cold or flu and even in the more serious situations such as cancer can be enhanced in these situations,” said Herzog.

The Garvan Institute study centres on two key events that enable the human body to recognise foreign substances and control invaders. When our body encounters a pathogen (bacteria and viruses), the immune cells retain and interrogate suspects. Their activation is made possible by NPY. These cells then return to the lymph nodes, which are found all over the body, with information about the foreign invaders. The lymph nodes are where decisions about defence are made.

“Most of us expect to come down with a cold or other illness when we are under pressure, but until now we have mostly had circumstantial evidence for a link between the brain and the immune system,” said lead Garvan researcher, associate Professor Fabienne Mackay. “During periods of stress, nerves release a lot of NPY and it gets into the bloodstream, where it directly impacts on the cells in the immune system that look out for and destroy pathogens (bacteria and viruses) in the body.”

In the case of bacteria and viruses, TH1 cells are part of the attack team that is sent out on the ‘search and destroy’ mission. But when their job is done they need to be turned ‘off’ and the immune system reset. The same hormone, NPY, that activates the sentry cells now prompts the TH1 cells to slow down and die.

“Under normal conditions, circulating immune cells produce small amounts of NPY, which enables the immune cells on sentry duty and the TH1 immune cells to operate – it’s a yin and yang kind of situation. But too much NPY means that the TH1 attack is prevented despite the foreign invaders being identified – and this is what happens during stress,” added McKay.

The impact of stress on the body has been observed in athletes. Ph. D researcher at the University of Queensland, Luke Spence, together with the Australian Institute of Sport, studied elite and recreational athletes over five months.

They found elite athletes were more susceptible to respiratory diseases under stress.

“A lot of elite athletes put themselves through vast amounts of physical stress in their training, but also their emotional, psychological stress of feeling the pressure of Australia on their shoulders, wanting to compete and wanting to do their best,” said Spence.

It’s not just athletes who are prone to stress. Pressures at work and at home may cause emotional and mental stress that can be equally damaging. Almost a third of all work absenteeism in Australia is due to illness, costing employers over $10 billion a year.

“I think it has a huge impact for the work force and also for employers – if their employees are constantly stressed, constantly under pressure, they are more likely to get sick,” Spence said.

Further research could lead to the development of new drugs which may inhibit the action of the neuropeptide Y hormone.

Herzog warns people to minimise stress before it becomes a problem.

“Relaxation methods like yoga will help you to prevent that but there will still be people out there that are not responding to that and treatment by interfering with the system will be important,” he said. “There’s obviously some time until such a treatment will be available but this is something we will definitely work towards.”

The Garvan research will be published in the Journal of Experimental Medicine, Volume 202, No. 11.

Tuesday, March 18, 2008

The leader of the 2008 Tour de Taiwan gets a yellow jersey. But every tour winner gets assistance from a “Miss Etiquette,” a tour assistant and a brand new part of the Tour de Taiwan. Miss Ettiquette has become a key feature at the awards ceremonies for every stage. Fma International Co., Ltd., the jersey sponsor of 2008 Tour de Taiwan, and a participant of the 2008 Taipei Cycle, has designed 4 different cheongsams (dresses) for “Miss Etiquette,” each matching the colors of the four leader jerseys. These cheongsam made a big hit with the Taiwanese and international media in Taiwan.

But what led to these champion jerseys and cheongsams? Wikinews Journalist Rico Shen visited the booth of Fma International and interviewed Martin Hsueh-po Cheng, General Manager of Fma International, to uncover the background of their design at the 3rd Day of Taipei Cycle, just after the finish of the 7th Stage of the Tour de Taiwan (March 15).

Thursday, February 21, 2008

Pula, Croatia – Blasts destroyed two vans owned by ethnic Albanian shop owners at two different locations in Pula, a city in the Croatian region of Istria. There were no injuries in the explosions and there was no responsibility attributed.

Relatives of the shop owners attributed the explosions to the present situation regarding the declaration of independence of Kosovo. There are some 2,000 ethnic Albanians in Istria.

Tuesday, January 24, 2006

Following the return of the Stardust space capsule from its encounter with the Comet Wild 2, NASA scientists have come up with a novel approach to dealing with the samples of “interstellar dust” that have been collected; they want help from the public.

The Stardust spacecraft carried an aerogel-based dust collector, which was exposed to space in varying orientations during different phases of the mission.

Only one side of the collector was exposed towards the stream of particles coming off the Comet Wild 2 during the encounter in 2004, while the other side was used to collect interstellar dust at an earlier point in the spacecraft’s journey.

Although scientists have seen the particles captured from comet Wild 2 when they examined the aerogel, they have not examined any of the particles expected on the other side of the collector due to their smallness. They will be examined after they are found with the help of Stardust@home. It is believed that on the order of 50 interstellar dust particles impacted the aerogel, each now resting inside a tiny crater.

Stardust traveled nearly three billion miles and its mission lasted seven years. At times it was traveling at 8 miles a second. Thats fast enough to go from San Francisco to Los Angeles in one minute.

Stardust set a new all-time record for being the fastest spacecraft to return to Earth, breaking the previous record set in May of 1969 during the return of the Apollo X(10) command module. Don Brownlee of the University of Washington, Seattle said “our spacecraft has traveled further than anything from Earth ever has – and came back. We went half-way to Jupiter to meet the comet and collect samples from it. But the comet actually came in from the outer edge of the solar system, out beyond the orbit of Neptune, out by Pluto.”

In a move similar to some distributed computing projects, the analysis work for the project will be spread among volunteers on the Internet, who are being asked to participate in this scientific undertaking.

Wikinews reporter Jason Safoutin investigated the Stardust@home project, and discussed its goals with one of its founders. Via email, he interviewed David P. Anderson, a founder of the SETI@home project, and one of the creators of the Virtual Microscope which will be used to search for captured particles from interstellar space.

I was wondering If I could get some questions answered or if you could give me some “insider” info for the project. I am aware that you are taking place in the development of the VM (Virtual Microscope)…Could I know more about that?The ‘virtual microscope’ lets you scan through a set of images as if you were turning the focus knob on a microscope. The images are fairly large (about 100 KB each) so it’s important to pre-load the images. While you’re looking through one set of images, the VM is busy downloading the JPEG files for the next set.

At first we thought we’d have to do this with a Java applet or Flash program – something tricky and complicated. My contribution was to point out that it could be done fairly easily using Javascript, and I wrote a prototype of this.

Will this project use the BOINC Platform/Program?

No. We thought about using some parts of BOINC (like the database and web pages for creating “accounts”) but it was easier just to do this from scratch.

How long will the project take?

It depends how many volunteers participate, and how fast they look at the ‘focus movies’. It will probably be just a month or two.

Anyone can join but they have to take a test before they can participate. What will the test include?

Looking at some focus movies and deciding whether they contain a dust particle. Participants see a lot of training examples before they take the test. It’s easy, not like a test in school.

How many will be allowed to participate?

No limit as of now.

When will the project start?

I think in about 2 months. It will take that long to transport the aerogel to the laboratory, and photograph it with the microscope. The software is ready to go.

Will the VM project analyze any of the particles or just look for them?

Stardust@home will only locate the particles. When they are located, they will be cut out of the aerogel and physically analyzed.

Thank you for your time David. And great work on the upcoming project and SETI@home.

A compilation of brief news reports for Monday, October 26, 2009.

A fatal car crash has killed a 79-year-old man Framingham, Massachusetts, United States, and seriously injured a woman. The woman is currently being held at Norwood, Massachusetts Hospital and is being treated for serious injuries. It was a single vehicle crash that happened on Route 1 on Saturday afternoon in Walpole, Massachusetts.

The car was heading south when it lost control and struck a utility pole just after 4 P.M. local time on Saturday. The man died at the scene.

Sources

• “Fatal car crash in Walpole” — NBC 10, October 25, 2009
• “Framingham man killed in Walpole car crash.” — Metro West Daily News, October 25, 2009

Ireland has pledged €1.35 million in emergency aid to Ethiopia, in order to help quell the ongoing food crisis in the country.

According to figures by the Ethiopian government released on Friday, the number of people needing food aid in the country is 6.2 million.

Irish Minister of State for Overseas Development Peter Power said that he was “deeply concerned” about the figures.

• “Ireland and Norway donate millions for Ethiopia emergency” — Jimma Times, October 24, 2009
• “€1.3m pledge for Ethiopian crisis” — Independent.ie, October 24, 2009